Vincristine-Dextran Complex Loaded Solid Lipid Nanoparticles for Drug Delivery to the Brain
نویسندگان
چکیده
The purpose of this work was to inspect the potential of vincristine-dextran complex loaded solid lipid nanoparticles for drug delivery to the brain. The nanoparticles were stained with a fluorescence dye and their plasma pharmacokinetic and brain concentrations were investigated following injection to rats. The result revealed a significant improvement in the plasma concentration profile of the SLN injected animals as well as a sharp increased concentration in the brains. Keywords—Brain, Coumarin-6, Nanoparticles, SLN.
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